Treatment Comparison

Wegovy vs. Mounjaro.

Understanding the difference between GLP-1 and dual-action therapies. Backed by clinical data, delivered by Jace Medical.

Wegovy®

The established GLP-1.

Active Ingredient

Semaglutide

Mechanism Action

Single Receptor (GLP-1)

Clinical Trial Weight Loss*

Average ~15%

Administration

Weekly Injection

Device Type (UK)

FlexTouch Pen (4 doses)

Mounjaro®

The dual-action innovation.

Active Ingredient

Tirzepatide

Mechanism Action

Dual Receptor (GLP-1 + GIP)

Clinical Trial Weight Loss*

Average up to 21% (at highest dose)

Administration

Weekly Injection

Device Type (UK)

KwikPen (4 doses - Multi-use)

*Based on respective clinical trial data (STEP 1 & SURMOUNT-1) over 68-72 weeks. Individual results vary.

The Science: One Key vs. Two.

Both medications are effective, but they work in slightly different ways to regulate your appetite and metabolism.

Wegovy targets satiety.

Mimics the GLP-1 hormone to signal fullness to your brain and slow stomach emptying. It's like having a single key that locks away your hunger.

Mounjaro targets satiety & metabolism.

Mimics both GLP-1 AND GIP hormones. This dual action may improve how your body breaks down sugar and fat. It's like having two keys for double the control.

Simple, discreet administration.

Both medications use easy-to-use injection pens.

FlexTouch Pen

Attach disposable needle.

Dial to prescribed dose.

Press and hold for 10s.

What about side effects?

Nausea & Digestion

Most common with both as your body adjusts. Usually subsides after a few weeks.

Injection Site

Some Mounjaro users report slightly more itchiness or redness at the injection spot.

How we help

Our clinicians titrate your dose slowly to minimise these effects.

Common Questions

Can I switch from Wegovy to Mounjaro?

Yes, but it requires a clinical review. You typically need to restart at a lower dose to manage tolerance and minimise side effects, as the medications work slightly differently.

Which one works faster?

Some clinical data suggests Mounjaro may show slightly faster initial weight loss results due to its dual-action mechanism targeting both GLP-1 and GIP receptors. However, both medications require patience and consistency.

Is one more expensive?

Starting doses are often similar in price, but higher maintenance doses can vary. Mounjaro's higher doses tend to be slightly more expensive than Wegovy's maintenance dose. Check our pricing page for current UK costs.

Still unsure which is right for you?

Our clinical team will review your health profile and recommend the safest, most effective option.

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