Clinical Comparison

Wegovy & Mounjaro

Understanding the difference between GLP-1 and dual-action therapies.
Backed by clinical data, delivered by Jace Medical.

Wegovy®

The Established GLP-1

Active Ingredient

Semaglutide

Mechanism

Single Receptor (GLP-1)

Clinical Weight Loss

Average ~15%

Device Type

FlexTouch Pen (4 Doses)

Mounjaro®

The Dual-Action Innovation

Active Ingredient

Tirzepatide

Mechanism

Dual Receptor (GLP-1 + GIP)

Clinical Weight Loss

Average ~21%

Device Type

KwikPen (Multi-use)

*Based on respective clinical trial data (STEP 1 & SURMOUNT-1). Individual results vary.

The Science: One Key vs. Two

Both medications mimic natural hormones, but they target different pathways in your metabolic system.

Wegovy (GLP-1)

Targets a single receptor in the brain to signal fullness and slow digestion. Think of it as a master key for satiety.

Mounjaro (GLP-1 + GIP)

Targets two receptors. It signals fullness AND improves how your body processes sugar and fat. Two keys for broader metabolic control.

Discreet Administration

Both treatments use simple, pre-filled injection pens.

FlexTouch

Weekly FlexTouch

1Attach needle
2Dial dose
3Inject (10s)

What about side effects?

Nausea & Digestion

Most common with both medications as your body adjusts to slower digestion.

Injection Site

Some Mounjaro users report slightly more redness or itching at the site than Wegovy users.

Clinical Support

We titrate your dose slowly. If side effects occur, our doctors adjust your plan immediately.

Common Questions

Can I switch from Wegovy to Mounjaro?

Yes, but it requires a clinical review. You typically need to restart at a lower dose to manage tolerance and minimise side effects, as the medications work slightly differently.

Which one works faster?

Some clinical data suggests Mounjaro may show slightly faster initial weight loss results due to its dual-action mechanism targeting both GLP-1 and GIP receptors. However, both medications require patience and consistency.

Is one more expensive?

Starting doses are often similar in price, but higher maintenance doses can vary. Mounjaro's higher doses tend to be slightly more expensive than Wegovy's maintenance dose. Check our pricing page for current UK costs.

Still unsure which is right for you?

Our clinical team will review your health profile and recommend the safest, most effective option.

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